While I was able to significantly lower my toxic burden particularly lead and mercury levels , things eventually plateaued, and although my levels were much improved, they were still way above what is considered acceptable. There is a bit of debate around the use of chelators, in particular DMPS, for detoxification, so I was looking for other methods.
Ron Hubbard disclaimer: no, I am not in any way affiliated with the Church of Scientology — I am simply interested in sweat and detox! Fortunately, my gym had a Sunlighten infrared sauna in the locker room. While I would have preferred a full-spectrum sauna Clearlight infrared saunas is another brand I recommend , it was low EMF and still provided the detox benefits of far infrared FIR. I would take the niacin three hours before getting in the sauna, and for 30 minutes prior to the sauna I would jog lightly on a treadmill followed by a few minutes on a vibration plate to bring up my body temperature and get my lymphatic system moving so I could begin sweating the instant I got in the sauna.
While in the sauna I would consume spring water with some added pink Himalayan salt to remain hydrated and assist with flushing toxins. At the end of each session I would jump immediately into a cold shower for minutes to close my pores. For this protocol, one must use the regular form of niacin full-flush and not a non-flushing variety. Not bad, but still a ways to go! Consistent use of an IR sauna will have more of an impact than niacin since niacin only targets fat.
My friends at InsideTracker also hooked me up with blood testing prior to and after my day detox. Given the high doses of niacin and other vitamins, I had concerns about putting extra stress on my liver.
Another thing to note about this method is that it is not a miracle solution like some people claim and that it has to be done over a period of time, preferably 2 — 5 days for maximum efficiency. Despite the fact that many people claim that this method does not work, it usually stems from the fact that the amount of time that the pills were taken for was not sufficient.
Taking a large dose of niacin pills in a short period of time, just before a drug test, often cause serious health problems then help pass said test. Only by giving it time will this method have the expected effect without the negative consequences.
Niacin Flush Detox Method. Table of Contents. However, our patient presented with hypoglycemia requiring IV dextrose infusion. Niacin causes hypoglycemia by inhibition of lipolysis and decreased production of free fatty acids which cannot be used as substrate for gluconeogenesis during prolonged fasting and starvation. Similar clinical scenarios were reported by Mittal et al. Niacin overdose has been classically associated with flushing and hepatotoxicity but in recent years, we have seen various other cases of niacin toxicity such as hypoglycemia and lactic acidosis.
These rare cases are likely to become more prevalent due to unregulated Internet-based health practices. As healthcare providers, we need to be more cautious while treating our patients. This case, while being a unique presentation of niacin toxicity also invites us to consider other significant aspects.
First, this case is a perfect example of the extensive role Internet nowadays plays in self-practiced healthcare especially by young adult population due to its uninhibited use. Second, lack of FDA regulations on nutritional and herbal supplements is quite concerning. As healthcare providers, we should be aware of the fact that our patients may be exposed to unreliable medical information leading to use of unrestricted drug paraphernalia resulting in increased incidence of various overdoses such as niacin with a myriad of clinical presentations.
We should, therefore, maintain a high degree of suspicion and should strive to keep ourselves updated about recent Internet-based health trends which are not scientifically proven but might be widely practiced by our patients. National Center for Biotechnology Information , U. Published online Apr Beenish Fayyaz , a Hafiz J. Rehman , b and Sunita Upreti b. Hafiz J. Author information Article notes Copyright and License information Disclaimer. Received Dec 19; Accepted Feb 6.
Introduction Niacin, a water-soluble vitamin, is used by physicians for treating dyslipidemias and pellagra caused by niacin deficiency. Table 1. Reported cases of niacin overdose in attempts to pass drug tests. Source Clinical features Ingested dose Outcome Paopairochanakorn et al.
Metabolic acidosis, hepatotoxicity Not reported Recovered Metabolic acidosis, hepatotoxicity, coagulopathy Not reported Recovered Mittal et al. Diabetic ketoacidosis, hepatotoxicity, prolonged QT interval. Metabolic acidosis, hypoglycemia, myopathy. Acute renal failure, haemolytic anaemia, thrombocytopenia. Acute Liver Failure. Not reported Recovered Sheila et al. Open in a separate window. Table 2. Serial laboratory findings of the patient. Table 3.
Formulations and dosage of niacin. Formulation Initial dose Maximum dose OTC availability Immediate release mg once daily 6 g daily in 3 divided doses Yes Sustained release mg once daily mg once daily Yes Extended release mg once daily 2 g once daily No. Case description A year-old gentleman with no previous medical history presented to our Emergency department with complaints of vomiting, diarrhoea, facial flushing, myalgias and palpitations. Discussion Niacin, also known as Nicotinic acid or Vitamin B3, is a water-soluble vitamin which is FDA approved for the treatment of dyslipidemia and niacin deficiency.
Conclusion This case, while being a unique presentation of niacin toxicity also invites us to consider other significant aspects. Disclosure statement No potential conflict of interest was reported by the authors. Recent advances in niacin and lipid metabolism. Curr Opin Lipidol. Evaluation and treatment of hypertriglyceridemia: an endocrine society clinical practice guideline.
J Clin Endocrinol Metab. Empirical studies assessing the quality of health information for consumers on the World Wide Web: a systemic review.
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