While there is no research defining the exact duration for a tolerance break, a study published in shows that after about 48 hours, the endocannabinoid receptors have already started to reset.
Finally, you can build a tolerance to both THC and to the specific strain of cannabis. Cannabis is a complex herbal medicine. Research shows that there are over chemicals and upwards of active compounds that have been isolated within the cannabis plant. These chemicals work very differently. CBD works through a myriad of neurotransmitters, enzymes and receptors.
Because THC acts directly on those receptors, too much THC can overwhelm the receptors and cause their functioning to be reduced. This is why you may need a tolerance break. The ECS is extremely important in the maintenance of homeostasis, or balance, within your body.
Having a well functioning ECS is important for optimal health. This deficiency is called clinical endocannabinoid deficiency. But, because THC works directly on the cannabinoid receptors it can overwhelm the system thus reducing the amount of cannabinoids your body produces naturally. Tolerance breaks can help reset the system to help it function optimally. A tolerance break is abstaining from using THC based cannabis products or medications for a period of time.
Because of how THC interacts with the body and receptors, at a certain stage, increasing your THC may have negative effects on your body as well as your ability to function. Some individuals feel strong effects when cutting out THC completely. The tolerance break itself is simple.
Choose a start and end date. And, during that time, do not take any THC containing cannabis products. Take a bit more cannabis each day or each dose and do this in a very mindful and reflective manner. If you follow this process, you should be able to get back to your original dose or even a bit lower and still have those therapeutic effects. Instead of increasing their dose, I might recommend a tolerance break. After the 48 hours, they can start at two milligrams of THC at night.
Cannabis causes fewer harms than some other drugs and creates less cravings. For those very reasons, ironically, some people find it challenging to find a balance with cannabis: they might think that cannabis has no harms and no cravings. Everything has pros and cons. And cannabis, like a lot of things, can create dependency.
A tolerance break is a good time to re-evaluate balance. If you want to stop completely, just continue the break. Others may return to cannabis and can use this as a support while bringing down their tolerance and finding better balance. Either way, a little support is a good thing. I hope you find it useful. If you don't I welcome your feedback.
Anyone who regularly consumes either medical or recreational cannabis, or both, will develop higher and higher tolerance to THC. This tolerance can be reduced by taking tolerance breaks. Tolerance is when the body becomes resistant to the effects of a substance or medication that is taken regularly. With repeated consumption, more of the substance is needed to achieve the original, desired effect. Like many other drugs and medicines, THC is consumed on a regular basis.
Tolerance is a very complex phenomenon and scientists don't fully understand the adaptations happening in our bodies when we experience it. The body's natural system that interacts with cannabis — our endocannabinoid system ECS — is a very dynamic and responsive system. As a result, more THC in the form of more frequent use or higher potency cannabis varieties is required to achieve the same results you experienced when you first started consuming.
While tolerance builds with continued regular use, research is inconclusive on how long it takes to develop. Animal studies have suggested that female rodents develop tolerance more rapidly than males , but this has been difficult to study in humans. The process is highly variable and depends on numerous factors such as consumption patterns, THC doses, routes of administration, and even genetic makeup. The universal standard is, if you notice that you need to increase the amount of cannabis you're using in order to feel its effects, you've built up a tolerance.
No, tolerance isn't necessarily a bad thing. Many medical patients wish to derive the benefits of THC pain relief, for instance , but they have a hard time dealing with THC's side effects of impairment and brain fog. Once a person develops a sufficient level of tolerance, it is possible to reap the medical benefits of cannabis in the absence of unwanted impairment.
Anecdotally, patients have reported that when they are first starting out on cannabis therapy, they have success taking THC right before bed. By sleeping through the intoxication for a week or two, they are slowly able to incorporate small amounts of THC into their daytime routine, capturing medical benefits with minimal side effects.
Tolerance breaks offer plentiful benefits with little effort. Moderating cannabis consumption by taking regular breaks is a good strategy for minimizing the risks of consuming too much THC. In the ECS, THC activates CB1 receptors in the brain's reward pathway, which triggers neurological responses that increase the likelihood a person will use cannabis again.
While technically there's nothing wrong with the fact that cannabis is a rewarding substance that makes people feel good, anything that creates the feeling of reward can be abused.
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